Dr. Oleksandr Shapoval is a scientific researcher at the Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, specializing in polymer-inorganic nanoparticles, functional colloids, and advanced nanosystems for multimodal imaging and therapeutic applications. He holds a Ph.D. in Chemistry with a focus on macromolecular compounds, along with degrees in chemistry, chemical technology, and administrative and financial management. His professional experience includes leading nationally funded research projects, contributing to commercial innovation initiatives, lecturing at academic institutions, and collaborating on international scientific programs involving the development of luminescent nanomarkers, functional nanoparticle shells, and advanced diagnostic probes. His research centers on the synthesis, surface engineering, and functionalization of lanthanide-based upconversion nanoparticles, with significant contributions to photodynamic therapy, multimodal bioimaging, colloidal stability studies, and targeted drug or photosensitizer delivery. He has authored numerous publications in high-impact journals and contributed to patented methods for preparing functionalized rare-earth nanoparticles. His work also includes extensive involvement in multidisciplinary project teams supported by national and international funding bodies, as well as leadership roles in projects related to imaging technologies and biomedical applications. Widely recognized for his research contributions, he has participated in prestigious scientific training programs, served as a co-investigator in collaborative initiatives, and contributed to advancements in nanodiagnostics, therapeutic systems, and polymer-based imaging agents.
Profile: ORCID
Featured Publications
Shapoval O.*, Poly(4-styrenesulfonic acid-co-maleic anhydride)-coated NaGdF₄-based nanoparticles with luminescence and magnetic properties for imaging of pancreatic islets and β-cells. ACS Appl. Mater. Interfaces, Accepted.
Shapoval O.*, Temoporfin-conjugated PEGylated poly(N,N-dimethylacrylamide)-coated upconversion colloid for NIR-induced photodynamic therapy of pancreatic cancer. Biomacromolecules, Published.
Shapoval O.*, PMVEMA-coated upconverting nanoparticles for upconversion-linked immunoassay of cardiac troponin. Talanta, Published.