Dr. E. Rajni Sabharwal, MD in Microbiology, is a leading researcher in clinical microbiology, antimicrobial resistance (AMR), and infection control. Her research focuses on emerging multidrug-resistant and extensively drug-resistant organisms, epidemiology of hospital-acquired infections, and antimicrobial susceptibility patterns in critical clinical settings, including urinary tract and bloodstream infections. She actively contributes to national multicentric studies on AMR surveillance and the implementation of antimicrobial and diagnostic stewardship programs, integrating One Health approaches. Dr. Sabharwal’s work encompasses molecular characterization of pathogens, synergy testing of novel antibiotic combinations, biofilm studies, and evaluation of rapid diagnostic tools to optimize patient management. Her publications address Gram-negative resistance, carbapenem-resistant Enterobacterales, Stenotrophomonas and MRSA infections, fungal pathogens, and empirical management strategies in tertiary care hospitals. She also investigates the role of immunotherapeutic interventions, such as SPAG9-primed dendritic cell-based vaccines, in gallbladder cancer. With expertise in epidemiological research, laboratory diagnostics, and clinical trial design, she has advanced knowledge on antimicrobial stewardship and resistance mitigation. Through workshops, symposia, and mentorship, Dr. Sabharwal promotes evidence-based practices, bridging clinical microbiology with public health strategies to combat AMR and improve patient outcomes, establishing her as a prominent contributor to infectious disease research and translational microbiology. (210 citations by ; 36 Documents; h-index: 8).